Brassica Tea and BroccoSprouts

Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice

Feeding broccoli sprout extracts providing daily doses of 10 mol of glucoraphanin to SKH-1 hairless mice with prior chronic exposure to UV radiation (30 mJ cm-2 of UVB, twice a week, for 17 weeks) inhibited the development of skin tumors during the subsequent 13 weeks; compared to the controls, tumor incidence, multiplicity, and volume were reduced by 25, 47, and 70%, respectively, in the animals that received the protective agent.

Article citation: Albena T. Dinkova-Kostova, Photochem. Photobiol. Sci., 2010, DOI: 10.1039/b9pp00130a

Authors: Albena T. Dinkova-Kostova, Jed W. Fahey, Andrea L. Benedict, Stephanie N. Jenkins, Lingxiang Ye, Scott L. Wehage and Paul Talalay

Share on Facebook

Filed under: Uncategorized on January 31st, 2010